Testing & quality

Mass spectrometry

Also known as: ms · mass spec · lc-ms

A method that measures molecular mass, used to confirm that a sample is the peptide it claims to be.

In plain terms

HPLC tells you how much of a sample is one substance. It cannot tell you which substance. Only mass spectrometry, comparing the observed mass against the theoretical mass for the stated sequence, confirms identity.

A COA with 99% purity and no MS data has established that the vial contains 99% of something.

Guides that use this term

How to read a peptide certificate of analysis

What a real certificate of analysis contains, why 99% purity does not mean 99% peptide, and the tells that separate a laboratory measurement from a marketing graphic.

Educational reference only. Pepperz does not provide medical advice, diagnosis, treatment, prescribing guidance, or dosing recommendations.