Preparation & administration
Maintenance dose
The steady dose taken once titration is complete and the intended effect has been reached.
In plain terms
Maintenance is not always the maximum studied dose. For GLP-1 drugs, a lower maintenance dose that is tolerated indefinitely usually outperforms a higher one that is abandoned.
Guides that use this term
One year after semaglutide was withdrawn, participants had regained two-thirds of the weight they lost, and their cardiometabolic gains reverted. The withdrawal trials, read honestly.
Microdosing semaglutide or tirzepatide is widely discussed and has never been tested in a randomised trial. Here is what exists, what does not, and why the distinction matters.
Facial gauntness after GLP-1 weight loss is caused by the weight loss, not by the drug. The same appearance follows rapid loss by any means — which is what the term obscures.
Educational reference only. Pepperz does not provide medical advice, diagnosis, treatment, prescribing guidance, or dosing recommendations.