Pharmacology & biology

GHRP

Also known as: growth hormone releasing peptide · ghrps

Growth hormone-releasing peptides — ghrelin-mimetic compounds that trigger growth hormone release through a different receptor than GHRH.

In plain terms

GHRPs act at the ghrelin receptor, not the GHRH receptor. Because the two pathways are separate, a GHRH analog and a GHRP together produce a larger pulse than either alone — the entire rationale for pairing CJC-1295 with ipamorelin.

The older GHRPs also stimulate appetite and, to varying degrees, cortisol and prolactin. Ipamorelin is prized in this class largely for being selective enough to avoid that.

Compounds where this comes up

Guides that use this term

Growth hormone secretagogues: what they can and can’t do

CJC-1295, ipamorelin and MK-677 reliably raise growth hormone and IGF-1 in humans. What the trials have not shown is that raising those numbers produces the outcomes people take them for.

Educational reference only. Pepperz does not provide medical advice, diagnosis, treatment, prescribing guidance, or dosing recommendations.