Testing & quality

Endotoxin

Also known as: lps · lal test · pyrogen

Bacterial cell-wall fragments that provoke fever and inflammation, detected by the LAL test — invisible to purity testing.

In plain terms

Endotoxin survives sterilisation. A solution can be sterile — containing no living bacteria — and still be loaded with endotoxin from bacteria that died earlier. Injecting it produces fever, chills, and inflammation.

HPLC purity tells you nothing about it. Endotoxin is measured by a separate assay entirely, and for injected material it belongs on the certificate.

Guides that use this term

How to read a peptide certificate of analysis

What a real certificate of analysis contains, why 99% purity does not mean 99% peptide, and the tells that separate a laboratory measurement from a marketing graphic.

Educational reference only. Pepperz does not provide medical advice, diagnosis, treatment, prescribing guidance, or dosing recommendations.