Peptide
Tesamorelin
Tesamorelin is a synthetic growth hormone-releasing factor analog used to reduce excess abdominal visceral fat in HIV-infected adults with lipodystrophy. It is given by subcutaneous injection and is not indicated for general weight loss; notable risks include fluid retention, glucose intolerance, elevated IGF-1, and injection-site reactions.
Detail
Overview
Tesamorelin is a synthetic growth hormone-releasing factor analog used to reduce excess abdominal visceral fat in HIV-infected adults with lipodystrophy. It is given by subcutaneous injection and is not indicated for general weight loss; notable risks include fluid retention, glucose intolerance, elevated IGF-1, and injection-site reactions.
Benefits, side effects, and protocols
Benefits list
- Reduces visceral abdominal fat
- May improve triglycerides and body composition
Side effects
- Injection site reactions
- Arthralgia
- Peripheral edema
- Glucose intolerance
Vendor protocol
- None listed
Clinical protocol
- 1.4 mg SC once daily
- 1.28 mg SC once daily
Evidence
- High
- FDA-approved for HIV-associated lipodystrophy; supported by randomized clinical trials showing visceral fat reduction.
Regulatory
- Fda Approved
- Prescription required
Research
Mechanisms
Evidence notes
- High
- FDA-approved for HIV-associated lipodystrophy; supported by randomized clinical trials showing visceral fat reduction.
Administration
Research links
Contraindications
- Active malignancy
- Pregnancy
- Hypothalamic-pituitary axis disruption
- Hypersensitivity to tesamorelin or excipients
Components
- None listed
Regulatory data
- Fda Approved
- Prescription required
Aliases
- Egrifta
- Egrifta SV
- Egrifta WR
- tesamorelin acetate
Used in these stacks
Related compounds
Half-life
How long does Tesamorelin stay in your system?
Half-life ≈ 8 minutes — see what remains after any number of days, and when it is practically cleared.
Educational reference only. Pepperz does not provide medical advice, diagnosis, treatment, prescribing guidance, or dosing recommendations. Sourcing Tesamorelin? Check your source before you use anything.