Preparation & administration
Units vs millilitres
Also known as: iu · insulin units · u-100
On a U-100 insulin syringe, 100 units = 1 mL. A unit is a volume, not a quantity of drug.
In plain terms
This is the most dangerous ambiguity in peptide dosing. "Take 10 units" is meaningless without knowing the concentration: 10 units of a vial reconstituted with 1 mL contains ten times the peptide of the same 10 units from a vial reconstituted with 10 mL.
Note that "IU" (international units) is a completely different concept — a measure of biological activity used for substances like growth hormone, unrelated to syringe markings that happen to share the word.
Why it matters
Never accept a dose expressed in units from someone who does not also know your reconstitution volume.
Guides that use this term
A “unit” on an insulin syringe is a volume, not an amount of drug. Here is how mg, mcg, mL and units relate — and why copying someone else’s unit count is the most dangerous shortcut in peptides.
Microdosing semaglutide or tirzepatide is widely discussed and has never been tested in a randomised trial. Here is what exists, what does not, and why the distinction matters.
Educational reference only. Pepperz does not provide medical advice, diagnosis, treatment, prescribing guidance, or dosing recommendations.