Cosmetic Peptide
GHK-Cu
GHK-Cu is a copper tripeptide used mainly in cosmetic skin-care formulations and studied for wound healing, skin repair, and wrinkle reduction. Human evidence is limited, and FDA has flagged compounded injectable use as a safety concern.
Injury HealingSkin RejuvenationTissue Regeneration
Detail
Overview
GHK-Cu is a copper tripeptide used mainly in cosmetic skin-care formulations and studied for wound healing, skin repair, and wrinkle reduction. Human evidence is limited, and FDA has flagged compounded injectable use as a safety concern.
Benefits list
- Wound healing
- Skin elasticity
- Wrinkle reduction
Side effects
- Local irritation
Vendor protocol
- Topical facial cream twice daily for 12 weeks
Clinical protocol
- Topical eye cream twice daily for 12 weeks
Evidence
- Low
- Cosmetic ingredient with limited human data; most support comes from skin, wound-healing, and mechanistic studies.
Regulatory
- Not Fda Approved
Research
Mechanisms
Collagen Synthesis
Evidence notes
- Low
- Cosmetic ingredient with limited human data; most support comes from skin, wound-healing, and mechanistic studies.
Administration
InjectableTopical
Research links
- https://pubchem.ncbi.nlm.nih.gov/compound/Copper-tripeptide
- https://pubmed.ncbi.nlm.nih.gov/26236730/
- https://www.fda.gov/drugs/human-drug-compounding/certain-bulk-drug-substances-use-compounding-may-present-significant-safety-risks
- https://www.cir-safety.org/sites/default/files/tripep032014tent.pdf
Contraindications
- None listed
Components
- None listed
Regulatory data
- Not Fda Approved
Aliases
- Copper tripeptide-1
- Copper peptide
- Tripeptide-1
- GHK copper
Educational reference only. Pepperz does not provide medical advice, diagnosis, treatment, prescribing guidance, or dosing recommendations.